Product Information
CAS number	67-64-1
EC index number	606-001-00-8
EC number	200-662-2
Grade	Ph Eur,BP,JPE,NF
Hill Formula	C₃H₆O
Chemical formula	CH₃COCH₃
Molar Mass	58.08 g/mol
HS Code	2914 11 00
Structure formula Image

Applications
Application	Acetone suitable for use as excipient EMPROVE® exp Ph Eur,BP,JPE,NF. Acetone chemical formula CH₃COCH₃, molar mass 58.08 g/mol and CAS No. 67-64-1.

Physicochemical Information
Boiling point	56.2 °C (1013 hPa)
Density	0.79 g/cm3 (20 °C)
Explosion limit	2.6 - 12.8 %(V)
Flash point	<-20 °C
Ignition temperature	465 °C DIN 51794
Melting Point	-95.4 °C
pH value	5 - 6 (395 g/l, H₂O, 20 °C)
Vapor pressure	233 hPa (20 °C)
Water absorption	1000 g/kg

Toxicological Information
LD 50 oral	LD50 Rat 5800 mg/kg
LD 50 dermal	LD50 Rabbit 20000 mg/kg

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H225: Highly flammable liquid and vapour. H319: Causes serious eye irritation. H336: May cause drowsiness or dizziness. EUH066: Repeated exposure may cause skin dryness or cracking.
Precautionary Statement(s)	P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P240: Ground/bond container and receiving equipment. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
RTECS	AL3150000
Storage class	3 Flammable liquids
WGK	WGK 1 slightly water endangering
Disposal	1 Strongly contaminated halogen-free organic solvents: container A.

Safety Information
Hazard Symbols	Flammable Irritant
Categories of danger	highly flammable, irritant
R Phrase	R 11-36-66-67 Highly flammable.Irritating to eyes.Repeated exposure may cause skin dryness or cracking.Vapours may cause drowsiness and dizziness.
S Phrase	S 9-16-26-46 Keep container in a well-ventilated place.Keep away from sources of ignition - No smoking.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.If swallowed, seek medical advice immediately and show this container or label.

Storage and Shipping Information
Storage	Store at +15 °C to +25 °C.

Transport Information
Declaration (railroad and road) ADR, RID	UN 1090 Aceton, 3, II
Declaration (transport by air) IATA-DGR	UN 1090 ACETONE, 3, II
Declaration (transport by sea) IMDG-Code	UN 1090 ACETONE, 3, II

Specifications
Assay (GC)	≥ 99.0 %
Identity (IR)	conforms
Identity B (Ph Eur)	conforms
Identity C (Ph Eur)	conforms
Identity B (NF)	conforms
Identity (JPE)	conforms
Water-insoluble substances	conforms
Appearance of solution	conforms
Acidity or alkalinity	conforms
Density (d 20 °C/20 °C)	0.790 - 0.793
Density (d 25 °C/25 °C)	≤ 0.789
Reducing substances	conforms
Readily oxidizable substances	conforms
Potassium permanganate-reducing substances	conforms
Phenole	conforms
Related substances (GC) (Methanol (Impurity A))	≤ 0.05 %
Related substances (GC) (2-Propanol (Impurity B))	≤ 0.05 %
Related substances (GC) (Benzene (Impurity C))	≤ 2 ppm
Related substances (GC) (other impurity)	≤ 0.05 %
Cyclohexane (residual solvent) (GC)	≤ 0.01 %
Other residual solvents (ICH Q3C)	excluded by the manufacturing process
Evaporation residue	≤ 0.0020 %
Water	≤ 0.30 %
Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present. Conforms to Ph Eur, BP, JPE, NF

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